PharmaClassified

Fragrances

Published: 09/27/2010

An aroma compound, also known as odorant, aroma, fragrance or flavor, is a chemical compound that has a smell or odor. A chemical compound has a smell or odor when two conditions are met: the compound needs to be volatile, so it can be transported to the olfactory system in the upper part of the nose, and it needs to be in a sufficiently high concentration to be able to interact with one or more of the olfactory receptors.

Aroma compounds can be found in food, wine, spices, perfumes, fragrance oils, and essential oils. For example, many form biochemically during ripening of fruits and other crops. In wines, most form as byproducts of fermentation. Odorants can also be added to a dangerous odorless substance, like propane, natural gas, or hydrogen, as a warning. Also, many of the aroma compounds play a significant role in the production of flavorants, which are used in the food service industry to flavor, improve, and generally increase the appeal of their products.

Aroma compounds classified by structure
Esters
Compound name
Fragrance
Natural occurrence
Chemical structure

Methyl formate
Ethereal



Methyl acetate
Sweet, nail polish
Solvent



Methyl butyrate
Methyl butanoate
Fruity, apple
Pineapple



Ethyl acetate
Sweet, solvent
Wine


Ethyl butyrate
Ethyl butanoate
Fruity, orange
Pineapple



Isoamyl acetate
Fruity, banana
Pear



Pentyl butyrate
Pentyl butanoate
Fruity, pear
Apricot



Pentyl pentanoate
Fruity, apple



Octyl acetate
Fruity, orange




Linear terpenes
Compound name
Fragrance
Natural occurrence
Chemical structure

Myrcene
Woody, complex
Verbena, bay


Geraniol
Rose, flowery
Geranium, lemon


Nerol
Sweet rose, flowery
Neroli, lemongrass


Citral, lemonal
Geranial, neral
Lemon
Lemon myrtle, lemongrass


Citronellal
Lemon
Lemongrass


Citronellol
Lemon
Lemongrass, rose
Pelargonium


Linalool
Floral, sweet
Woody, lavender
Coriander, sweet basil
Lavender


Nerolidol
Woody, fresh bark
Neroli, ginger
Jasmine



Cyclic terpenes
Compound name
Fragrance
Natural occurrence
Chemical structure

Limonene
Orange
Orange, lemon


Camphor
Camphor
Camphor laurel


Terpineol
Lilac
Lilac, cajuput


alpha-Ionone
Violet, woody
Violet


Thujone
Minty
Cypress, lilac
Juniper



Aromatic
Compound name
Fragrance
Natural occurrence
Chemical structure

Benzaldehyde
Almond



Eugenol
Clove
Clove


Cinnamaldehyde
Cinnamon
Cassia
Cinnamon


Ethyl maltol
Cooked fruit
Caramelized sugar



Vanillin
Vanilla
Vanilla


Anisole
Anise
Anise


Anethole
Anise
Anise
Sweet basil

Estragole
Tarragon
Tarragon


Thymol
Thyme
Thyme



Amines
Compound name
Fragrance
Natural occurrence
Chemical structure

Trimethylamine
Fishy
Ammonia



Putrescine
Diaminobutane
Rotting flesh
Rotting flesh


Cadaverine
Rotting flesh
Rotting flesh


Pyridine
Fishy



Indole
Fecal
Flowery
Feces
Jasmine


Skatole
Fecal
Feces



Other aroma compounds
Alcohols
Furaneol (strawberry)
1-Hexanol (herbaceous, woody)
cis-3-Hexen-1-ol (fresh cut grass)
Menthol (peppermint)
Aldehydes
Acetaldehyde (pungent)
Hexanal (green, grassy)
cis-3-Hexenal (green tomatoes)
Furfural (burnt oats)
Esters
Fructone (fruity, apple-like)
Hexyl acetate (apple, floral, fruity)
Ethyl methylphenylglycidate (strawberry)
Ketones
Dihydrojasmone (fruity woody floral)
Oct-1-en-3-one (blood, metallic, mushroom-like)[1]
2-Acetyl-1-pyrroline (fresh bread, jasmine rice)
6-Acetyl-2,3,4,5-tetrahydropyridine (fresh bread, tortillas, popcorn)
Lactones
gamma-Decalactone intense peach flavor
gamma-Nonalactone coconut odor, popular in suntan lotions
delta-Octalactone creamy note
Jasmine lactone powerful fatty fruity peach and apricot
Massoia lactone powerful creamy coconut
Wine lactone sweet coconut odor
Sotolon (maple syrup, curry, fenugreek)
Thiols
Ethanethiol, commonly called Ethyl mercaptan (added to propane or other liquefied petroleum gases used as fuel gases)
Grapefruit mercaptan (grapefruit)
Methanethiol, commonly called Methyl mercaptan (Durian or leek)
2-Methyl-2-propanethiol, commonly called tertiary-butyl mercaptan is added as a blend of other components to natural gas used as fuel gas.
Miscellaneous compounds
Methylphosphine and dimethylphosphine (garlic-metallic, two of the most potent odorants known)[1]
Nerolin (orange flowers)
Tetrahydrothiophene (added to natural gas)
2,4,6-Trichloroanisole (cork taint)
Substituted pyrazines
Aroma compound receptors
Animals which are capable of smell detect aroma compounds with olfactory receptors. Olfactory receptors are cell membrane receptors on the surface of sensory neurons in the olfactory system which detect air-borne aroma compounds.

In mammals, olfactory receptors are expressed on the surface of the olfactory epithelium in the nasal cavity.



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